Jump to main content jump to navigation nature. buy generic viagra online Com homepage publications a-z index browse by subject my account e-alert sign up register subscribe login cart search advanced search journal home > archive > review > full text > table 2 table 2 | targeted agents that produce responses in sarcoma from the following article: advances in sarcoma genomics and new therapeutic targets barry s. where to buy viagra in the usa Taylor, jordi barretina, robert g. buy cheap viagra Maki, cristina r. qual e o melhor viagra ou viagra Antonescu, samuel singer & marc ladanyi nature reviews cancer 11, 541-557 (august 2011) doi:10. buy viagra without prescription 1038/nrc3087 back to article | back to figures and tables | previous table agent tumour types known alteration or recognized or proposed target approximate response rate refs imatinib gist* kit and pdgfrî± mutations ~80% 126 dermatofibrosarcoma protuberans col1a1–pdgfî² fusions high 132,133 tenosynovial giant cell tumour and pigmented villonodular synovitis col6a3–csf1 fusions high 200 sunitinib imatinib-resistant gist kit mutations ~8% 201 desmoid tumour and deep fibromatosis unknown unknown 202 alveolar soft-part sarcoma aspl–tfe3 fusion unknown 145 sorafenib angiosarcoma vegfr2 mutations, vegf or its receptors ~15% 129 desmoid tumour and deep fibromatosis unknown high 203 denosumab giant-cell tumour of bone rank ligand moderate 204 crizotinib inflammatory myofibroblastic tumour alk fusions unknown 205 met inhibitor alveolar soft-part sarcoma aspl–tfe3 fusion unknown 38,206 clear-cell sarcoma ews–atf1 fusions unknown 134,135,206 igf1r antibody solitary fibrous tumour-haemangiopericytoma igf1r and vegfr, and igf2 overexpression unknown 207,208 ewing's sarcoma ews–fli1 or ews–erg 10–15% 137,138,139 bevacizumab angiosarcoma vegfr2 mutations, vegf or its receptors ~15% 73,129,143,209 cediranib alveolar soft-part sarcoma aspl–tfe3 fusion unknown large integer pazopanib synovial sarcoma unknown ~15% cardinal mtor inhibitors pecomas and related conditions lymphangioleiomyomatosis and angiomyolipoma mtor high 146,147,148 alk, anaplastic lymphoma receptor tyrosine kinase; aspl, alveolar soft part sarcoma locus; atf1, activating transcription factor 1; col1a1, collagen type iî±1; col6a3, collagen type viî±3; csf1, colony-stimulating factor 1; ews, ewing sarcoma breakpoint region 1; fli1, friend leukaemia virus integration 1; gist, gastrointestinal stromal tumour; igf, insulin-like growth factor; igf1r, insulin-like growth factor 1 receptor; pdgfr, platelet-derived growth factor receptor; pecoma, perivascular epithelioid cell tumour; tfe3, transcription factor binding to ighm enhancer 3; tsc2, tuberin; vegfr, vascular endothelial growth factor receptor. viagra covered by insurance but not birth control *dasatinib and sorafenib are also indicated for kit-mutant gist. qual e o melhor viagra ou viagra Download file if the slide opens in your browser, select "file > save as" to save it. http://classicmotocrossimages.com/mbs-viagra-for-sale-generic-im/ Download high-resolution power point slide (141 kb) back to article | back to figures and tables | previous table top nature reviews cancer issn :. viagra pills discount viagra    
 
 
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